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A matter of heart

Dear Friend,

"A matter of heart"

Those of you who've been with me for a while know that Regenerizer started out as a compound to help fight the fatigue and muscle toxicity associated with the statin drugs.

It then wound up in the hands of athletes who loved it. Eventually we found it to be a great sex enhancer and depression fighter too.

Lately I have had some success with it as an adjunctive (added to regular treatment) for heart failure.

This actually makes perfect sense. If it helps athletes improve their cardiac performance, why wouldn't it help a sick heart too?

Well my friend, the proof as they say is in the pudding.

There actually have been some studies using Coq 10 alone (one of the main ingredients in Regenerizer).

No one has ever tried the combo as it exists in Regenerizer and I am not equipped to do randomized double blinded placebo controlled studies in my office yet, but the results are intriguing.

First let's refresh your memory.



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The heart is the most important organ in the body. Without it the brain cannot function. If the brain is damaged temporarily but the heart is ok, the person might survive and return to a normal level of function depending on the extent of the damage.

A normal brain with a dead or dying heart equals a dead brain in 3 minutes or less!

Heart disease remains the Number One Killer in this country, and the number one focus of many anti-aging doctors and traditional medical doctors alike.

In the past Co q 10 has been tested for its effects in heart failure. Many of the studies have been positive, and a few have been negative.

In looking at the negative studies, I found several things that were of interest to me.

Number one was the journals they were published in. These were universally 'traditional " medical journals. While there were positive studies published in this type of journal too you could almost predict the outcome before you read the study.

Next, the people running the study were not vitamin people. Many of them had financial ties to Big Pharmacy.

We have seen several examples of that in the past year and of course they got huge press. The biggest offender is JAMA whom I call the guardian of the old boy network in medicine.

They printed the article damming vitamin , an article representing a study so poorly done they never would have published it were it for any thing but a vitamin.

There are other examples but believe me in a few years its going to be like "Gone with the Wind" in their offices unless they do a abrupt change of heart on Vitamins.

Supplementation would be here to stay if the American people have anything to say about it.

Sadly as you know from the Codex and other legal machinations the Government may side with the boys from JAMA.

Surprise surprise.

Back to the negative studies.

Finally and again universally, the dosages they were using were way to small (30 mg) or less and were not the gel form of Co Q 10 (those of you who have Regenerizer know that the Co Q 10 is in the red gel caps).

In most of the positive heart failure studies, the dosage used was 100mg or greater.

Here is a nice study that review what I have already said above and confirms it independently.

Again, if you hate reading studies, read the last 3 or 4 "punch" lines.

1: Biofactors. 2003;18(1-4):91-100.

Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure.

Rosenfeldt F, Hilton D, Pepe S, Krum H.

Cardiac Surgical Research Unit, Alfred Hospital and Baker Institute, Melbourne, Victoria, Australia. f.rosenfeldt@alfred.org.au

COENZYME Q10 IN PHYSICAL EXERCISE. We identified eleven studies in which CoQ10 was tested for an effect on exercise capacity, six showed a modest improvement in exercise capacity with CoQ10 supplementation but five showed no effect. CoQ10 IN HYPERTENSION. We identified eight published trials of CoQ10 in hypertension. Altogether in the eight studies the mean decrease in systolic blood pressure was 16 mm Hg and in diastolic blood pressure, 10 mm Hg. Being devoid of significant side effects CoQ10 may have a role as an adjunct or alternative to conventional agents in the treatment of hypertension. CoQ10 IN HEART FAILURE. We performed a randomised double blind placebo-controlled pilot trial of CoQ10 therapy in 35 patients with heart failure. Over 3 months, in the CoQ10 patients but not in the placebo patients there were significant improvements in symptom class and a trend towards improvements in exercise time

META-ANALYSIS OF RANDOMISED TRIALS OF COENZYME Q10 IN HEART FAILURE. In nine randomised trials of CoQ10 in heart failure published up to 2003 there were significant trends towards increased ejection fraction and reduced mortality. There were sufficient numbers of patients for meaningful results.

Bottom line, positive effects in high blood pressure, heart failure and exercise.

There are more references at the end of this article, but here is a real life live fire story from my clinic: Minnie is 82 years old and as had high blood pressure for much of her adult life. She also had a heart attack 2 years ago and since that time had been experiencing worsening shortness of breath with activity and occasional difficulty sleeping flat. She also suffered from extreme fatigue.

She has seen the Cardiologists and been on "Maximal " therapy for her heart failure which was diagnosed by ultrasound and of course clinically.

She was graded as a New York Heart Association Class 3 which in English means she could walk around her house a bit but would usually have to stop and rest a minute or two quite often.

She graded the quality of her life as "poor" since she could do very little without shortness of breath.

We started her on Regenerizer 2 packs a day. Within 3 to 4 weeks she noticed far less fatigue, a better mental attitude, and increased ability to do her daily activities without as much breathing difficulty.

She saw her Cardiologist in follow up and was told that it was not the Regenerizer, but the prescription drugs which were "finally kicking in" (after 1 year of not working!!!).

Further she was told to stop taking that "expensive garbage". A higher dose of a drug called an ACE inhibitor was added.

3 weeks later her kidneys had all but shut down and she required emergency treatment for elevated potassium.

She survived all that somehow and was released form the hospital on no ACE inhibitor.

She went back on the Regenerizer and is doing just fine again.

I am in the process of trying to convince her to give her Cardiologists another try!!!

While a few success stories does not a study make, the rationale is clear that adding Carnitene and DHEA to Co q 10 as we have in Regenerizer has implications for the treatment of medical disease as well as the maintenance of great health and long life!!!

Best, Doc

Don't forget, Regenerizer is back too and it's going fast so move now! I doubt our supply will last through the weekend. Get some while we still have it and avoid lengthy back orders. Click on: http://drdavesbest.com/regenerizer.html

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Dr. Dave’s Best is located at:
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Copyright 2005



More references:

The following study makes its recommendation based on safety data.

1: J Cardiovasc Nurs. 2002 Jul;16(4):9-20.

Coenzyme Q10 and cardiovascular disease: a review.

Sarter B.

Department of Nursing, University of Southern California, Los Angeles, California, USA.

This article provides a comprehensive review of 30 years of research on the use of coenzyme Q10 in prevention and treatment of cardiovascular disease. This endogenous antioxidant has potential for use in prevention and treatment of cardiovascular disease, particularly hypertension, hyperlipidemia, coronary artery disease, and heart failure. It appears that levels of coenzyme Q10 are decreased during therapy with HMG-CoA reductase inhibitors, gemfibrozil, Adriamycin, and certain beta blockers. Further clinical trials are warranted, but because of its low toxicity it may be appropriate to recommend coenzyme Q10 to select patients as an adjunct to conventional treatment.

The next study show actual cases of people who lived longer and felt better on Co Q therapy:

1: Conn Med. 1997 Nov;61(11):707-11.

Coenzyme Q10: a vital therapeutic nutrient for the heart with special application in congestive heart failure.

Sinatra ST.

Manchester Hospital.

Vitamin coenzyme Q10 is a critical adjuvant complementary therapy for patients with congestive heart failure, especially when traditional medical therapy is unsuccessful. The following case studies, with systolic and/or diastolic dysfunction, demonstrate the effectiveness of coenzyme Q10 in improving quality of life, as well as survival.

Publication Types: Case Reports




Dave Woynarowski, M.D., CPT
The Nation's #1 Anti-Aging Physician


P.S. For the worlds best anti-aging supplements including Dr Dave's Best Pharmaceutical Grade Fish Oil go here and order now. Don't delay; you are not getting any younger, YET!



       

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