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The World's Top Anti-Aging Specialist |
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The Difference Between Men and WomenDear Friend,Way back when, when I was in my Internal Medicine residency we would often be up all night. Sometimes we would be just waiting for the next disaster and trying to kill time so the pressure would not get to us. Oft times in the wee hours of the morning the pressure and the sleep deprivation would give way to a unique brand of medical silliness that to this day remains unnamed. Basically we would combine rare medical conditions with everyday occurrences and see if there was any way to make them easier to remember in case they ever walked through our doors. One night the topic ventured in to the area of hermaphrodism, that is ambiguous sex often caused by genetic mutations or abnormal enzyme function that made it hard to tell if a person was truly male or female. The workup was time consuming, expensive and often left us quite confused. So we devised simple social tests that would cost little and were based on typical behaviors of each sex. One such discriminating test was the phone bill. This was based on the generalization that women tended to talk more on the phone than men. Then there was the shopping issue. Take the subject and place him/her in front of a hardware store on the left and a shoe store on the right. The resultant choice had to give at least a 90% chance of giving the right sex. If all else failed I came up with the be all and end all...the test to end all tests which I aptly name "The 3 Stooges Test". Place the subject in front of the television. Turn on the 3 Stooges. Observe behavior. Laughter and the need to imitate the behavior of the 3 stooges strongly suggested male sex. Staying for more than one episode was a dead give away. Disgust confusion or a comment like, "I don't get it, what is funny about that?" had a 99% specificity for females. So after that long intro I want to share a quote from the 3 Stooges with you that relates to our knowledge of Omega 3 Fatty acids and Fish Oil. Larry to Moe," You know Fish Is great Brain food!" Moe to Larry, " You know you should fish for a Whale!" Please no emails, ladies, telling me that whales are not fish but actually mammals! Before you leave ladies, rest assure there will be no more 3 stooges quotes and that the rest of this email directly bears on a subject that is probably near and dear to you: the health of your children. Recently a study asked the question, " Is it possible to boost the natural intellectual capacity of a child using food or food supplements?" A woman named Nicola Graimes reviewed this and other studies in her book "Brain Food for Kids" which I highly recommend for all mothers or mothers to be or for that matter all grandmothers whose daughters are mothers! Specifically cited were studies done by Dr Alex Richardson at Oxford and Dr Madeline Portwood an educational psychologist at Durham. 140 pupils from 12 primary schools were supplemented with Fish Oil. After 6 months on the oil, there was 40% improvements in multiple factors including concentration, reading skills writing and get this! General Behavior. This calls to mind a previous study I reported on from Britain where 200 of the most serious offenders in a prison were given fish oil supplements. At the end of 6 months there was a 30+% decrease in serious offenses and overall behavior scores.
Other studies I referenced showed decrease in hostility and improved concentration during stress and things like exam periods. While I am not suggesting an Orwellian approach to modifying behavior, I am saying that people will behave "more like their true selves" when supplemented with Fish Oil. One important point that I will continue to harp on as long as there are people out there who oppose me on it. These studies were done with FISH OIL not fish. It is in vogue for nutritionists to insist that people eat "whole foods" instead of taking supplements. I will state again for the record my opinion of this. NONSENSE! If you need higher doses of fish oil and intend to get it by eating fish instead of taking fish oil supplements, then you better love the taste of fish and mercury and lead and polybiphenyl compounds, etc. If you need higher doses of fish oil then you better love the taste of fish and mercury and lead and polybiphenyl compounds etc. Could you stomach 5 salmon meals a day to get 3 grams of fish oil. Do you want to expose yourself and your family to all those pollutants? I personally know of a nutritionist who gobbles my fish oil like there is no tomorrow, but continues to insist in her newsletters that you must eat fish. Go figure! Another quick reminder: Plants are a lousy source of long chain fatty acids that people need. Flax, pumpkin and soy all contain varying degrees of Omega 3 fatty acids but much to the dismay of people who sell them, they require extensive conversion in the body which is very inefficient and produces little useable Omega 3 fatty acids. All the Best from the King of Pharmaceutical Grade Fish Oil, Dr Dave! Dr Dave's Best Fish Oil contains no detectable amounts of heart harming mercury, lead, PVC's or PBC's. It is tested for radiation, purified and concentrated and remains the industry benchmark. No other Fish Oil can come close. See the numerous testimonials on the site. To experience the amazing and multiple benefits of Dr Dave's Best Pharmaceutical Grade Fish Oil go to the site and order NOW! For the worlds best anti-aging supplements including Dr Dave’s Best Pharmaceutical Grade Fish Oil and the one and only Regenerizer And order now. Don’t delay; you are not getting any younger, YET! Endurance hit the shelves on August 13th Just in time for the games of the XXVIII Olympiad! This amazing new compound is finally available. You can get all of its benefits RIGHT NOW, so go to the site and order the Chinese secret that floods your body with INSTANT ENDURANCE!!! These statements are consistent with the research and findings about the compounds in Instant Endurance and Regenerizer from the viewpoint of Traditional Chinese Medicine, Western laboratory medicine and Olympic coaches. They have not been evaluated by the FDA. Notify your own doctor of all herbal and nutraceutical supplements you are taking and let him/her be your guide, even if they have no clue about the subject!!!! Do not stop or change any medicines you are taking without the expressed consent of your own personal physician. Copyright 2007 References: 1: Prig Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):233-9. A randomized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties. Richardso AJ, Puri BK. University Department of Physiology, Oxford, England, UK. alex.richardson@physiol.ox.ac.uk (1) The authors tested the prediction that relative deficiencies in highly unsaturated fatty acids (HUFAs) may underlie some of the behavioral and learning problems associated with attention-deficit/hyperactivity disorder (ADHD) by studying the effects of HUFA supplementation on ADHD-related symptoms in children with specific learning difficulties (mainly dyslexia) who also showed ADHD features. (2) Forty-one children aged 8-12 years with both specific learning difficulties and above-average ADHD ratings were randomly allocated to HUFA supplementation or placebo for 12 weeks. (3) At both baseline and follow-up, a range of behavioral and learning problems associated with ADHD was assessed using standardized parent rating scales. (4) At baseline, the groups did not differ, but after 12 weeks mean scores for cognitive problems and general behavior problems were significantly lower for the group treated with HUFA than for the placebo group; there were significant improvements from baseline on 7 out of 14 scales for active treatment, compared with none for placebo. Group differences in change scores all favored HUFA, reaching conventional significance levels for 3 out of 14 scales. (5) HUFA supplementation appears to reduce ADHD-related symptoms in children with specific learning difficulties. Given the safety and tolerability of this simple treatment, results from this pilot study strongly support the case for further investigations. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 11817499 [PubMed - indexed for MEDLINE] 1: Prostaglandins Leukot Essent Fatty Acids. 2000 Jul-Aug;63(1-2):1-9. Fatty acid metabolism in neurodevelopmental disorder: a new perspective on associations between attention-deficit/hyperactivity disorder, dyslexia, dyspraxia and the autistic spectrum. Richardson AJ, Ross MA. University Laboratory of Physiology, Oxford, UK. alex.richardson@physiol.ox.ac.uk There is increasing evidence that abnormalities of fatty acid and membrane phospholipid metabolism play a part in a wide range of neurodevelopmental and psychiatric disorders. This proposal is discussed here in relation to attention-deficit/hyperactivity disorder (ADHD), dyslexia, developmental coordination disorder (dyspraxia) and the autistic spectrum. These are among the most common neurodevelopmental disorders of childhood, with significant implications for society as well as for those directly affected. However, controversy still surrounds both the identification and management of these conditions, and while their aetiology is recognized as being complex and multifactorial, little progress has yet been made in elucidating predisposing factors at the biological level.An overview is provided here of the contents of this Special Issue, which contains a selection of reports from a unique multidisciplinary workshop involving both researchers and clinicians. Its purpose was to explore the possibility that ADHD, dyslexia, dyspraxia and autism fall within a phospholipid spectrum of disorders. This proposal could explain the high degree of co-morbidity between these conditions, their aggregation within families and relation to other psychiatric disorders, and a range of associated features that are already well known at a clinical level. The existing evidence for fatty acid abnormalities in these disorders is summarized, and new approaches are outlined that have the potential to improve both the identification and the management of these and related neurodevelopmental and psychiatric conditions. Copyright 2000 Harcourt Publishers Ltd. Publication Types: Review Review, Tutorial PMID: 10970706 [PubMed - indexed for MEDLINE] 1: Nutr Neurosci. 2004 Apr;7(2):91-9. Effects of fish oil on the central nervous system: a new potential antidepressant? Naliwaiko K, Araujo RL, da Fonseca RV, Castilho JC, Andreatini R, Bellissimo MI, Oliveira BH, Martins EF, Curi R, Fernandes LC, Ferraz AC. Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Fisiologia e Farmacologia, Universidade Federal do Parana, 81.531-990 Curitiba, PR, Brazil. In the last 100 years major depression has increased worldwide. In this study we provided coconut fat (CF, rich in saturated fatty acids) or fish oil (FO, rich in n-3 polyunsaturated fatty acids) to female rats throughout pregnancy and lactation and then to their offspring post-weaning and examined lipid brain profile and the possible effect of FO as antidepressant agent in the offspring in adulthood (F1). Rats were submitted to forced swimming test, elevated plus maze, Morris water maze and open field. Peroxidation rate in the cerebral cortex and hippocampus were measured. Docosahexaenoic acid (DHA) concentration in dam's milk, eicosapentaenoic acid (EPA) and DHA concentration in hippocampus and cerebral cortex from F1 rats FO supplemented increased significantly when compared to control (C) and CF rats. Arachidonic acid/EPA ratio in the cerebral cortex and hippocampus decreased in rats submitted to forced swimming test. Peroxidation rate were not different between the groups. Immobility time in the forced swimming test in FO group was reduced (p < 0.01) when compared to C and CF rats. We conclude that lifelong intake of FO was able to induce an antidepressant effect with EPA and DHA concentration increased in the cerebral cortex and hippocampus. PMID: 15279495 [PubMed - indexed for MEDLINE] 1: J Lipid Res. 2004 Jun;45(6):1112-21. Epub 2004 Apr 01. Omega-3 fatty acid ethyl-eicosapentaenoate, but not soybean oil, attenuates memory impairment induced by central IL-1beta administration. Song C, Horrobin D. Neuroscience Division, Department of Psychiatry, University of British Columbia, 2255 Westbrook Mall, Vancouver, BC Canada V6T 2A1. caisong@interchange.ubc.ca Proinflammatory cytokine interleukin (IL)-1beta can cause cognitive impairment, activate the hypothalamic-pituitary-adrenal axis and impair monoaminergic neurotransmission in the rat. IL-1beta has also been shown to increase the concentration of the inflammatory mediator prostaglandin E2 (PGE2) in the blood. Omega (n)-3 fatty acids, such as eicosapentaenoic acid (EPA), which are components of fish oil, have been shown to reduce both the proinflammatory cytokines and the synthesis of PGE2. The purpose of this study was to determine whether dietary supplements of EPA would attenuate the inflammation-induced impairment of spatial memory by centrally administered IL-1beta. Rats were fed with a diet of coconut oil (contained a negligible quantity of fatty acids), soybean oil (contained mainly n-6 fatty acids), or a diet of coconut oil enriched with ethyl-EPA (E-EPA). The rats were then injected intracerebroventricularly with IL-1beta or saline. The results of this study demonstrated that the IL-1-induced deficit in spatial memory was correlated with an impairment of central noradrenergic and serotonergic (but not dopaminergic) function and an increase in the serum corticosterone concentration. IL-1beta also caused an increase in the hippocampal PGE2 concentration. These effects of IL-1 were attenuated by the chronic administration of E-EPA. By contrast, rats fed with the soybean oil diet showed no effect on the changes induced by the IL-1 administration. PMID: 15060086 [PubMed - in process] Dr Dave's comment: Fish Oil worked, soy oil did not! All the Best From the King of Pharmaceutical Grade Fish Oil  Dave Woynarowski, M.D., CPT The Nation's #1 Anti-Aging Physician P.S. For the worlds best anti-aging supplements including Dr Dave's Best Pharmaceutical Grade Fish Oil go here and order now. Don't delay; you are not getting any younger, YET! 
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