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![]() The World's Top Anti-Aging Specialist |
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Fish oil and Depression Part 2Dear Friend,Ok folks! Now let's examine why fish Oil makes a natural choice to use for depression and other mood disorders. For review, yesterday we talked about how a large part of the brain especially the membranes of the nerves there are made up of Essential Fatty Acids. We examined how investigators have found roles for Fish Oil in various Brain related disorders including Alzheimer's Disease, ADD, autism, schizophrenia, hostility, anxiety, borderline, and bipolar disorders in this and other emails! We discussed the Omega 6 to Omega 3 ratio which the Journal of the American college of Nutrition suggests should be 1:1 ( J. AM. Coll. Nutr. 1999;18:487-489 Simopoulos). It is now 20:1 or above thus high lighting the need for HIGH DOSE Fish Oil to correct it! So now let's take a simplistic look at how Fish Oil may enhance the treatment of Major and minor depression from a biochemical point of view.
If you want to look at brain function in a depressed patient vs. those of a normal non- depressed person you can use several imaging studies including MRI and PET scanning. You can also use chemical uptake and turn around studies that use sugar and other biochemical markers of cellular activity and respiration. If you look at the very specific places in the brain where depression causes biochemical abnormalities (Limbic system, Nucleus accumens, and certain other areas of the frontal lobe), you find that certain chemicals are either lacking in absolute amount, or not released properly. Once you treat with Fish Oil, those biochemical abnormalities often reverse. Additionally several areas of the brain show decreased blood flow and decreased use of sugar, both indicators of low function. Fish Oil usage reverses those abnormalities as well in studies. Other studies have showed that in depression actual areas of the brain atrophy or shrink leading to the loss of nervous tissue. In other words brain cells die! In the past no one ever thought you could regenerate new brain cells, but this is exactly what Fish Oil promotes. This is also the probable reason it works in Alzheimer's as well! High amounts of physical and emotional stress can activate pro-inflammatory chemicals in the brain as well as he body that interfere with the cell's ability to bind vital brain transmitters like dopamine and serotonin ( see yesterdays' email!). By now you are well versed in knowing how Fish Oil can decrease the amount of inflammation in the body and brain, thus combating the problem of the bad effects of too much Omega 6 or too much stress. If you look at the nerve cells themselves 2 amazing things become apparent. In addition to needing Fish Oil's component fatty acids to be in their membranes, they actually secrete DHA and bathe themselves in it! Next if you look at the activity of the nerve cell to signal the next cell in line (ultimately how the brain works!) low omega 3's in the diet reduce this activity (synaptic) by over 40%! Some of you take DHEA and Phosphotidyl Serine for memory and thinking effects. Fish Oil enhances the endogenous production of these vital neuro-hormonal transmitters. Low Omega 3 in the diet results in a 35% decrease in the brain's ability to produce Phosphatidyl Serine which has anti-depressant activity of its own! Omega 3 fatty acids also increase the density and number of serotonin receptors in the frontal cortex. Recall that the SSRI's which stands for Selective Serotonin Reuptake Inhibitors, block the breakdown of serotonin effectively doing the same thing but with tons more side effects. Another study found that high dose fish oil supplementation(15X greater than the usual dose) blocked the activity of the enzyme that breaks down the key neurotransmitter Dopamine. This enzyme called MAO-B is the target for another effective but potentially deadly class of drugs called MAO inhibitors. In all studies Fish Oil supplementation was deemed extraordinarily safe. But then why wouldn't it be, Mother Nature put it here for us to use! One specific case study placed a "Treatment Resistant" patient who had failed all the regular drugs on Fish Oil 4grams a day. Within 1 month there where major subjective and objective improvements in their depression. Measured chemical parameters improved and the size of the brain actually grew as measured by the MRI! (Br, J, of Psychiatry 200;176:421-428.) There are several major studies using Omega 3 Fatty Acids in humans. The success rate is around 85% of these studies. Negative trials tended to use DHA alone. This reinforces my earlier statements about not separating these 2 vital components of Fish Oil One note, researchers discovered that Flaxseed oil had the potential to cause mania, hypomania and other untoward behavioral abnormalities when substituted for Fish Oil in the treatment of depression. One more reason to avoid Flax Oil! As far as dosages go, I'd recommend you start on the high side e.g. 6 capsules a day at least, especially if you are suffering from more severe depression. Fish Oil can also augment the activity of almost every class of anti-depressant drug, so they can be taken together. Remember depression can be a very serious illness. I personally like the way fish Oil keeps my moods up, my creativity high my memory sharp and my energy roaring (along with Regenerizer and Instant Endurance!). But then again I am not typically depressed. If you are depressed get your doctors help! Folks you have to pardon me if I gloat just a little bit over the recent news releases about Fish Oil. What I am talking about it a whole slew of "Officially Sanctioned Governmentally Approved Bodies" owning up to the fact that Fish Oil is an essential part of everyone's diet for tons of reasons. Recall a few weeks ago the American Cancer Society finally prevailed upon the FDA to allow nutrient content claims for foods and supplements containing Fish Oil in the fight against several cancers notably Breast, Prostate, And Colon Cancer to name but a few. Once every 5 years a government appointed committee releases its findings. These findings are called Dietary Guidelines for Americans This panel of nutritional experts released the actual guidelines in January of 2005 but the word is already out that Omega 3 fatty acids (fish oils) are recommended to reduce the incidence of heart disease, the leading cause of death in this country. Next the Department of Health and Human Services released its report admitting also that Fish Oil reduces heart disease. Recently released info from the prestigious Mayo Clinic a bastion of Traditional Medicine and no friend of anti-aging medicine, suggests that fish oil can be helpful in not only reducing heart disuse, but Blood Pressure as well as the effects of stress on the human body. They also suggested that anyone on any of the low carb diets, especially Atkins is not getting enough Omega 3 fatty acids. The American heart Association also admits that there is some serious potential danger to consuming fish which are mercury laden. Why am I telling you al of this? Most of you have heard it before from me. The answer lies in the phrase, "you've heard it from me." Everyday I suffer the professional slings and arrows of my colleagues who insist that there can be no benefit to supplementation in spite of all the evidence I have presented. Everyday a few of my readers email me with snide remarks about how my supplement must be snake oil; it can't possibly be that good. It also took a tractor trailer load full of hard scientific evidence to convince all of the above organizations about Fish Oil's benefits. I should know, most of it is in my house!! On the flip side I get far more positive comments and testimonials from folks who absolutely love the product and are committed to staying on it. Those of you who not yet tried it probably never will. There is nothing I can do to convince you. However if you believe in government agencies and their ability to provide useful unbiased information for the good of the public, then today's email is for you! My very first newsletter was entitled "Ancient Natural Food Supplement Yields Astounding Benefits in Modern Man...Modern Science Begrudgingly acknowledges many benefits, more benefits than Any Prescription Drug." And I might add without the side effects. Well the medical and governmental establishments are still fighting tooth and nail to cling to their outdated philosophies. But now they have a mutiny on their hands, or at least a "Riot in the Dungeons" with their own appointed committees having to the face facts about all the health benefits Fish Oil can give to you. All the Best, Dr Dave To experience the amazing and multiple benefits of Dr Dave's Best Pharmaceutical Grade Fish Oil go to the site and order NOW! Dr Dave's Best Pharmaceutical Grade Fish Oil For the worlds best anti-aging supplements including Dr Dave’s Best Pharmaceutical Grade Fish Oil and the one and only Regenerizer go to: http://www.drdavesbest.com/frontend/proddetail.aspx?pn=DDB-RG And order now. Don’t delay; you are not getting any younger, YET! Some other Dr Dave's Best Products designed to help you get the most out of Life! 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And extraordinary health begins with the right foundation. As a doctor, I know the importance a good multi-vitamin can have on your health. And I wouldn't recommend one to you...until now. An exclusive multi-vite is now available and provides your body with essential ingredients that are the foundation for extraordinary health. Because of the work of 3 leading anti-aging doctors, every ingredient and the roles they play in interacting with each other was comprehensively researched. To ensure that you're getting a superior multi-vite that begins to reverse the aging process, follow this link. I think you'll agree with me that it's superior to every other multi-vitamin. Click this link and decide for yourself. Instant Brain Power: How This Doctor's New Breakthrough Keeps Your Mind Sharp And Improves Creativity, Memory & Recall No Matter What Your Age At last! A doctor approved, all natural product that significantly boosts your memory, recall and overall mental sharpness. From teenagers with exams to adults dealing with a variety of issues, a focused, creative and sharp mind is vital to a healthy lifestyle. Conclusive studies, my personal experience and countless hours of researching and testing have shown the ingredients in this new product are guaranteed to bring results. What can it do for you? Follow this link for free documentation and the reasons why it's essential. Just go here: Dr. Dave’s Best is located at: 1050 D Maidencreek Road Fleetwood, PA 19522 Phone Orders: 24-Hour Order Line: 866-654-7670 Fax: 610-916-3931. Dr Dave's Best makes no claims to treat mitigate or diagnose any disease with any of the products listed on our site, past present or future! Copyright 2005 Major Review: Alternative Medicine Review Vol 8 # 4 2003 pp410-425. Prostaglandins Leukot. E.F.A. 2004 Jul;71 (1) :13-18 ![]() Dave Woynarowski, M.D., CPT The Nation's #1 Anti-Aging Physician P.S. For the worlds best anti-aging supplements including Dr Dave's Best Pharmaceutical Grade Fish Oil go here and order now. Don't delay; you are not getting any younger, YET!
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